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COVID-19 (30)80 ± 51.315 (50.0)15 (50.0)29 (96.7)1 (3.33)14 (46.7)16 (53.3)5 (16.7)25 (83.3)9 (30.0)21 (70.0)4 (13.3)26 (86.7)1 (33.3)29 (96.7)18 (60.0)12 (40.0)Have contact but negative results (25)suspected but negative 56.8 ± 51.010 (40.0)15 (60.0)25 (100)0 (0)6 (24.0)19 (76.0)6 (24.0)19 (76.0)6 (24.0)19 (76.0)3 (12.0)22 (88.0)0 (0)25 (100)12 (48.0)13 (52.0)FeverCoughFever and coughFever or cough624as psychologic fever (1).Children with a COVID-19 diagnosis had contact with family (19), school (2), nursery (6), karate school (2), and unknown (1). Those who had contact with COVID-19 but a negative test result reported only contacts with family (23) and school (2).Finally, we calculated the sensitivity and speci-ficity of fever, cough, fever and cough, and fever or cough to distinguish COVID-19-positive and COVID-19-negative children. Sensitivity of fever, cough, fever and cough, and fever or cough are 0.45, 0.18, 0.09, and 0.54, respectively. Specificity of them are 0.15, 0.52, 0.63, and 0.03, respectively (Table 2). Age (months)Sex Boy (%) Girl (%)Contact with COVID-19 Yes (%) No (%)Fever Yes (%) No (%)CoughRhinorrheaDiarrheaPneumoniaAny symptoms**: We excluded children who suspected COVID-19 but were not COVID-19 because they were suspected of COVID-19 because of fever.Table 1　Results of comparisons between three groupsCOVID-19 was We conducted a study of COVID-19 in Japanese children at one of the largest admitting hospitals for COVID-19 patients in Tokyo. We could not find differences in symptoms between children with COVID-19 and children who had close contact but negative SARS-CoV-2 test results. On the other Table 2　Sensitivity and specificity of symptomsSymptomsSpecificityresult (51)63.9 ± 55.30.220.2424 (47.1)27 (52.9)<0.050 (0)51 (100)<0.0544 (86.3)7 (13.7)<0.0523 (45.1)28 (54.9)0.5710 (19.6)41 (80.4)0.927 (13.7)44 (86.3)0.136 (11.8)45 (88.2)0.53Sensitivity0.450.180.090.54p0.150.520.630.03Discussion