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although further studies are required to validate our data. Additionally, we could learn historical changes in anesthesia practice for patients under-going LGS at our institute.AcknowledgementsThe authors thank staffs of the Department of Anesthesiology and Pain Medicine and Department of Obstetrics and Gynecology, Juntendo University Hospital for supporting this work over many years and providing the authors with valuable cases.No funding was received.Author contributionsOK collected data. OK and MH analyzed data. OK wrote the first draft of the manuscript. MH edited the manuscript. All authors read and approved the final manuscript.Conflicts of interest statementThe authors declare that they have no conflict of interest associated with this manuscript. 1) Gan TJ, Belani KG, Bergese S, et al: Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesth Analg, 2020; 131: 411-448. 2) Eriksson H, Korttila K: Recovery profile after desflu-rane with or without ondansetron compared with propofol in patients undergoing outpatient gynecolog-ical laparoscopy. Anesth Analg, 1996; 82: 533-538. 3) Park JH, Lee C, Shin Y, An JH, Ban JS, Lee JH: Compar-ison of oxycodone and fentanyl for postoperative patient-controlled analgesia after laparoscopic gyneco-logical surgery. Korean J Anesthesiol, 2015; 68: 153-158. 4) Kasagi Y, Hayashida M. Sugasawa Y, et al: Antiemetic effect of naloxone in combination with dexamethasone and droperidol in patients undergoing laparoscopic gynecological surgery. J Anesth, 2013; 27: 879-884. 5) Kranke P, Apefel CC, Papenfuss T, et al: An increased body mass index is no risk factor for postoperative nausea and vomiting. A systematic review and results of original data. Acta Anaesthesiol Scand, 2001; 45: 160-166. 6) Barrow PM, Hughes DG, Redfern N, Urie J: Influence of droperidol on nausea and vomiting during patient- controlled analgesia. Br J Anaesth, 1994; 72: 460-461. 7) Hirata I, Iwamoto M, Matsui H, Yoshinuma H, Funa-koshi R: Droperidol Reduces Postoperative Nausea and Vomiting and Supports the Continuation of Intrave-nous Patient-Controlled Analgesia with Fentanyl. J Pharm Pharm Sci, 2020; 23: 220-230. 8) Lo Y, Chia YY, Liu K, Ko NH: Morphine sparing with droperidol in patient-controlled analgesia. J Clin Anesth, 2005; 17: 271-275. 9) Tramèr NR, Fuchs-Buder T: Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis: a system-atic review. Br J Anaesth, 1999; 82: 379-386.10) Cheng CR, Sessler DI, Apfel CC: Does Neostigmine Administration Produce a Clinically Important Increase in Postoperative Nausea and Vomiting? Anesth Analg, 2005; 101: 1349-1355.11) Hood DD, Eisenach JC, Tuttle R: Phase I safety assess-ment of intrathecal neostigmine methylsulfate in humans. Anesthesiology, 1995; 82: 331-343.12) Baciarello M, Cornini A, Zasa M, et al: Intrathecal atro-pine to prevent postoperative nausea and vomiting after Cesarean section: a randomized, controlled trial. Minerva Anestesiol, 2011; 77: 781-788.13) Proakis AG, Harris GB: Comparative penetration of glycopyrrolate and atropine across the blood-brain and placental barriers in anesthetized dogs. Anesthesi-ology, 1978; 48: 339-344.14) Sumikura H, van de Velde M, Tateda T: Comparison between a disposable and an electronic PCA device for labor epidural analgesia. J Anesth, 2004; 18: 262-266.15) Mugita M, Kawahara R, Tamai Y, et al: Effectiveness of ultrasound-guided transversus abdominis plane block and rectus sheath block in pain control and recovery after gynecological transumbilical single-in-cision laparoscopic surgery. Clin Exp Obstet Gynecol, 2014; 41: 627-632.16) Taniguchi H, Nagahuchi M, Kamada T, et al: Effect of scheduled intravenous acetaminophen on postopera-tive nausea and vomiting in patients undergoing lapa-roscopic gynecologic surgery. J Anesth, 2020; 34: 502- 511.17) Carron M, Zarantonello F, Tellaroli P, Ori C: Efficacy and safety of sugammadex compared to neostigmine for reversal of neuromuscular blockade: a meta-anal-ysis of randomized controlled trials. J Clin Anesth, 2016; 35: 1-12.589FundingReferences

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