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10) Sekine I, Shintani Y, Shukuya T, Takayama K, Inoue A, Okamoto I, Kiura K, Takahashi K, Dosaka-Akita H, Takiguchi Y, Miyaoka E, Okumura M, Yoshino I: A Japanese lung cancer registry study on demographics and treatment modalities in medically treated patients. Cancer Sci, 2020; 111: 1685-1691. 11) Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Brewin J, Roberts N, Harada N, Atsuta R, Takahashi K, Mori K, Fujisawa T, Shirai T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez F, Shaw D, Pavord ID, Thomas M: Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and indi‑vidual patient data meta-analysis. Eur Respir J, 2020; 55: 1902150.＊ 12) Okamoto S, Suzuki K, Hayashi T, Muraki K, Nagaoka T, Nishino K, Sekimoto Y, Sasaki S, Takahashi K, Seyama K: Transbronchial lung biopsy for the diagnosis of lymphangioleio‑myomatosis: the severity of cystic lung destruction assessed by the modified Goddard scoring system as a predictor for establishing the diagnosis. Orphanet J Rare Dis, 2020; 15: 125. 13) Hayashi T, Takamochi K, Kohsaka S, Kishi‑kawa S, Suehara Y, Takahashi F, Suzuki K, Saito T: Spontaneous transformation from EGFR/PTEN co-mutated lung adenocarci‑noma to small cell carcinoma in lymph node metastasis. Pathol Int, 2020; 70: 295-299. 14) Kohsaka S, Hayashi T, Nagano M, Ueno T, Kojima S, Kawazu M, Shiraishi Y, Kishikawa S, Suehara Y, Takahashi F, Takahashi K, Suzuki K, Takamochi K, Mano H: Identifica‑tion of Novel CD74-NRG2αFusion From Comprehensive Profiling of Lung Adenocar‑cinoma in Japanese Never or Light Smokers. J Thorac Oncol, 2020; 15: 948-961. 15) Kozuki T, Nogami N, Hataji O, Tsunezuka Y, Seki N, Harada T, Fujimoto N, Bessho A, Takamura K, Takahashi K, Satouchi M, Kato T, Shukuya T, Yamashita N, Okamoto H, Shinkai T: Thoracic Oncology Research Group: Open-label, multicenter, randomized phase II study on docetaxel plus bevacizumab or pemetrexed plus bevacizumab for treatment of elderly (aged ≥75 years) patients with previously untreated advanced non-squamous non-small cell lung cancer: TORG1323. Transl Lung Cancer Res, 2020; 9: 459-470. 16) Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Terao C, Amar‑iuta T, Gazal S, Kochi Y, Horikoshi M, Suzuki K, Ito K, Koyama S, Ozaki K, Niida S, Sakata Y, Sakata Y, Kohno T, Shiraishi K, Momo‑zawa Y, Hirata M, Matsuda K, Ikeda M, Iwata N, Ikegawa S, Kou I, Tanaka T, Nakagawa H, Suzuki A, Hirota T, Tamari M, Chayama K, Miki D, Mori M, Nagayama S, Daigo Y, Miki Y, Katagiri T, Ogawa O, Obara W, Ito H, Yoshida T, Imoto I, Takahashi T, Tanikawa C, Suzuki T, Sinozaki N, Minami S, Yama‑guchi H, Asai S, Takahashi Y, Yamaji K, Takahashi K, Fujioka T, Takata R, Yanai H, Masumoto A, Koretsune Y, Kutsumi H, Higashiyama M, Murayama S, Minegishi N, Suzuki K, Tanno K, Shimizu A, Yamaji T, Iwasaki M, Sawada N, Uemura H, Tanaka K, Naito M, Sasaki M, Wakai K, Tsugane S, Yamamoto M, Yamamoto K, Murakami Y, Nakamura Y, Raychaudhuri S, Inazawa J, Yamauchi T, Kadowaki T, Kubo M, Kamatani Y: Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nat Genet, 2020; 52: 669-679.＊ 17) Ihara H, Mitsuishi Y, Kato M, Takahashi F, Tajima K, Hayashi T, Hidayat M, Winardi W, Wirawan A, Hayakawa D, Kanamori K, Matsumoto N, Yae T, Sato T, Sasaki S, Taka‑mochi K, Suehara Y, Ogura D, Niwa SI, Suzuki K, Takahashi K: Nintedanib Inhibits Epithelial-Mesenchymal Transition in A549 Alveolar Epithelial Cells Through Regulation of the TGF-β/Smad Pathway. Respir Investig, 2020; 58: 275-284. 18) Sakamoto S, Kataoka K, Kondo Y, Kato M, Okamoto M, Mukae H, Bando M, Suda T, Yatera K, Tanino Y, Kishaba T, Hattori N, Taguchi Y, Saito T, Nishioka Y, Kuwano K, Kishi K, Inase N, Sasaki S, Takizawa H, Johkoh T, Sakai F, Homma S: Diffuse Lung Diseases Research Group of the Ministry of Health, Labour and Welfare, Japan. Pirfeni‑done plus inhaled N-acetylcysteine for idio‑527