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5210330 MaleFemaleCeUtMtLtAe Gender22210014232020421Relationship between serum LR11 levels and survivalWe compared overall survival of 39 patients in the low LR11 group and seven patients in the high LR11 group using the Kaplan-Meier estimate. Results showed that the 5-year survival rate was 41% in the low LR11 group and 14.3% in the high LR11 group, with a significantly worse prognosis for the high LR11 group (p=0.012, Figure 8).LR11 was discovered by Jiang et al. in 2008 as an important factor involved in the differentiation of degree of venous invasion into v0, v1, v2, and v3 (Figure 5). There were no significant differences between these groups.Relationship between serum LR11 levels and blood biochemistryWe examined the correlation between each of the blood biochemistry findings, as TP, Alb, TG, and T-Cho with serum LR11 levels; however, the results showed no significant differences for each value (Figure 6, 7).Main tumor location*Histologic type   Squamous cell carcinoma   Carcinosarcoma   Malignant melanomaDepth of tumor invasion**Lymph node metastasis**pStage**Ce: Cervical esophagus, Ut: Upper thoracic esophagus, Mt: Middle thoracic esophagus,Lt: Lower thoracic esophagus, Ae: Abdominal esophagus, Well: Well differentiated squamous cell carcinoma,Mod: moderately differentiated squamous cell carcinoma, Poor: poorly differentiated squamous cell carcinoma*: Japan Esophageal, S; Japanese Classification of Esophageal Cancer, 11th Edition**: UICC TNM Classification of Malignant Tumours, 7th edNS: Not SignificantTable 1 Clinicopathological backgroundWellModPoorpT1pT2pT3pT4N0N1N2N3ⅠⅡⅢⅣ NSNSNSNSNSNS515Low-level group (n)345071911215184111471441212114811164High-level group (n)Discussion

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