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2)Department of Orthopedics, Juntendo University Nerima Hospital, Tokyo, Japan3)Department of Orthopedics, Juntendo University Juntendo Hospital, Tokyo, JapanHironori OCHI2), Suguru KATO2), Muneaki ISHIJIMA3)Corresponding author: Koji Namiki (ORCID: 0000-0001-8574-1817)Department of Orthopedics, Juntendo University2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, JapanTEL: +81-3-3924-5931 / 090-5210-0307　E-mail: m0106054@yahoo.co.jp〔Received　Dec. 30, 2021〕〔Accepted　Jun. 20, 2022〕J-STAGE Advance published date: Sep. 9, 2022Copyright © 2022 The Juntendo Medical Society. This is an open access article distributed under the terms of Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original source is properly credited. doi: 10.14789/jmj.JMJ21-0056-OAObjectives: Postoperative venous thromboembolism is an important peri-operative complication associated with total hip arthroplasty (THA). In particular, early detection of deep venous thrombosis (DVT) is important for the prevention of pulmonary embolism (PE). However, the methods and timing of examinations for DVT detection differ among the facilities. This study aimed to clarify the time, site, and frequency of DVT after THA.Materials and Methods: Background characteristics including age, sex, body mass index, diagnosis, operation type, operation time, and anesthesia type were investigated in 348 patients who underwent THA at our hospital between April 2017 and April 2019. Blood tests were performed preoperatively and on postoperative days (POD) 0, 1, 3, 7, 14, and 21. Simultaneously, vascular ultrasonography was performed to investigate the time and site of thrombus occurrence before and after the surgery.Results: DVT was observed in 27.2% of the patients on POD 21. The DVT-positive ratio was 9.4% (6/64) in males and 31.3% (89/284) in females. There was a significant difference between the groups (p = 0.0002). Patients in the DVT-positive group were significantly older than those in the DVT-negative group (73.0 ± 7.9 years vs. 63.3 ± 11.2 years, p = 0.0041). DVT mainly occurred in the soleal vein (74.7%). However, there was no significant difference between the operated and non-operated sides. In the DVT-positive group, thrombus occurred in 13.3% of preoperative cases, 20.0% on POD 0, 46.7% on POD 1, 13.3% on POD 3, 6.7% on POD 7, and 0% on POD 14 and 21.Conclusions: Vascular ultrasonography showed that thrombus occurred most frequently in the soleal vein. Thrombus occurred in 66.6% of DVT-positive patients by POD 1, indicating that thrombus appeared very early after surgery. All thrombus cases were formed by POD 7.Key words: deep venous thrombosis (DVT), pulmonary embolism (PE), ultrasonography, total hip arthroplasty (THA)Juntendo Medical Journal2022. 68(5), 491-498Original ArticlesAppearance and Frequency of Deep Venous Thrombosis After Total Hip ArthroplastyIntroductionOwing to the current trend in aging societies, the number of total hip arthroplasty (THA) operations will increase in the future. THA is associated with various peri-operative complications, among which postoperative venous thromboembolism (VTE) is particularly important.VTE combines deep venous thrombosis (DVT) and pulmonary embolism (PE). DVT is caused by 1)Department of Orthopedics, Juntendo University Graduate School of Medicine, Tokyo, Japanthrombus formation in deep veins such as the iliac, femoral, popliteal, and lower leg veins. Thrombus release from the deep veins can be considered a cause of PE. After release, the thrombus flows into the bloodstream, passes through the right atrium and ventricle, and embolizes the pulmonary artery. The frequency of DVT diagnosed by venography without prophylaxis in patients who have under-gone THA was estimated to be 40-60% in the 7th American College of Chest Physicians (ACCP) 491Koji NAMIKI1), Masahiko NOZAWA2), Sung-gon KIM2), Yuko SAKAMOTO2),