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) Yamaguchi K, Yamazaki S, Kumakura S, Someya A, Iseki M, Inada E, Nagaoka I: Yoku-kansan, a Japanese herbal medicine, suppresses substance P-induced production of inter-leukin-6 and interleukin-8 by human U373 MG glioblastoma astrocytoma cells. Endocr. Metab. Immune. Disord. Drug Targets, 2020; 20: 1073-1080.) Kumagai Y, Murakami T, Kuwahara-Arai K, Iba T, Reich T, Nagaoka I: Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils. Innate. Immun, 2020; 26: 565-579.) Nagaoka I, Tamura H, Reich J: Therapeutic potential of cathelicidin peptide LL-37, an antimicrobial agent, in a murine sepsis model. Int. J. Mol. Sci, 2020; 21: 5973.) Nagaoka I, Hu Z, Hosoda H, Kumagai Y: Therapeutic action of antimicrobial catheli-cidin peptide LL-37 on a murine sepsis model. Juntendo Med. J, 2020; 66: 297-311.) Yamazawa T, Ogawa H, Murayama T, Yama-guchi M, Oyamada H, Suzuki J, Kurebayashi N, Kanemaru K, Oguchi K, Sakurai T, Iino M: Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics. J Gen Physiol, 2020; 152: e201812235.) Yamashita Y, Suzuki C, Uchiyama Y, Nagata S: Infertility caused by inefficient apoptotic germ cell clearance in Xkr8-deficient male mice. Mol Cell Biol, 2020; 40: e00402-19.) Nozaki Y, Kato Y, Uike K, Yamamura K, Kikuchi M, Yasuda M, Ohno S, Horie M, Murayama T, Kurebayashi N, Horigome H: Co-phenotype of left ventricular non-com-paction cardiomyopathy and atypical cate-cholaminergic polymorphic ventricular tachy-cardia in association with R169Q, a ryanodine receptor type 2 missense mutation. Circ J, 2020; 84: 226-234.† 4) Zhou X, Park KH, Yamazaki D, Lin PH, Nishi M, Ma Z, Qiu L, Murayama T, Zou X, Takeshima H, Zhou J, Ma J: TRIC-A channel maintains store calcium handling by interacting with type 2 ryanodine receptor in cardiac muscle. Circ Res, 2020; 126: 417-435.＊ 5) Sakairi H, Kamikubo Y, Abe M, Ikeda K, Ichiki A, Tabata T, Kano M, Sakurai T: G Protein-Coupled Glutamate and GABA Recep-tors Form Complexes and Mutually Modu-late Their Signals. ACS Chem Neurosci, 2020; 11: 567-578.) Takahashi S, Hanaoka K, Okubo Y, Echizen H, Ikeno T, Komatsu T, Ueno T, Hirose K, Iino M, Nagano T, Urano Y: Rational design of a near-infrared fluorescence probe for Ca2+ based on phosphorus-substituted rhodamines utilizing photoinduced electron transfer. Chem Asian J, 2020; 15: 524-530.) Okubo Y, Iino M, Hirose K: Store-operated Ca2+ entry-dependent Ca2+ refilling in the endoplasmic reticulum in astrocytes. Biochem Biophys Res Commun, 2020; 522: 1003-1008.) Saito K, Murayama T, Hata T, Kobayashi T, Shibata K, Kazuno S, Fujimura T, Sakurai T, Toyoshima Y: Conformational diversity of dynactin sidearm and domain organization of its subunit p150. Mol Biol Cell, 2020; 31: 1218-1231.) Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T: Phos-phorylation of CRMP2 is required for migra-tion and positioning of Purkinje cells: Redun-dant roles of CRMP1 and CRMP4. Brain Res, 2020; 1736: 146762. 6 7 8 9 10) Oliva Trejo JA, Tanida I, Suzuki C, Kakuta S, Tada N, Uchiyama Y: Characterization of starvation-induced autophagy in cerebellar Purkinje cells of pHluorin-mKate2-human LC3B transgenic mice. Sci Rep, 2020; 10: 9643. 11) Iyer KA, Hu Y, Nayak AR, Kurebayashi N, Murayama T, Samsó M: Structural mecha-nism of two gain-of-function cardiac and 293Biochemistry and Systems Biomedicine〈Original Articles〉 1 2＊ 3) Yamagishi Y, Someya A, Nagaoka I: Citrul-line cooperatively exerts an anti-inflamma-tory effect on synovial cells with glucosamine and N-acetylglucosamine. Biomed. Rep, 2020; 13: 37-42.〈Reviews〉 1 2Cellular and Molecular Pharmacology〈Original Articles〉 1 2 3