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Rs)RRRRRRRRRRRRRRRRRRR222424222421≤0.51≤0.5≤0.5≤0.5≤0.51≤0.52≤0.5111111112>20.250.2520.250.120.250.120.2544120.5110.520.5RRRRRRRRRR(a) Host-immune system modulators.150strainsMPIPCa)ABPCb)CEZc)CMZd)FMOXe)IPMf)GMg)ABKh)MINOi)CFXj)EMk)CLDMl)VCMm)TEICn)LZDo)FOMp)STq)LVFXr)IDSA1IDSA2IDSA3IDSA5IDSA6IDSA8IDSA 13IDSA 17IDSA 20IDSA 44(a) oxacillin, (b) ampicillin, (c) cefazolin, (d) cefmetazole, (e) flomoxef, (f) imipenem, (g) gentamicin, (h) arbekacin, (i) minocycline, (j) cefoxitin, (k) erythromycin (l) clindamycin, (m) vancomycin, (n) teicoplanin, (o) linezolid, (p) fosfomycin (q)sulfamethoxazole/trimethoprim, (r) levofloxacin (s) resistance.strainsSCCmecTypeIDSA1typeIII(3A)IDSA2typeV(5C2&5)ST97IDSA3typeV(5C2&5)ST789IDSA5typeIII(3A)IDSA6IDSA8IDSA 13typeV(5C2&5)ST789mecAtypeIVd(2B)ST672typeV(5C2&5)ST789IDSA 17typeV(5C2&5)ST789typeV(5C2&5)ST789typeVc(5C2&5)ST30IDSA 20IDSA 44(a) Sequence type. (b) gyrA, parC, fusA and dfrB genes are not resistance genes per se. Point mutations in these genes confer resistance.strainsIDSA1IDSA2IDSA3IDSA5IDSA6IDSA8IDSA 13IDSA 17IDSA 20IDSA 44Table 1　Minimum inhibitory concentrations of the MRSA strains analyzed in this study. Numbers are in μg/mlTable 2　Drug resistance genes found in the MRSA strains analyzed in this studyTable 3　Virulence determinants found in the MRSA strains analyzed in this study>16>32>16>3284>16>32888>16842884168>16>164>16482224>8>80.5>80.52ST(ab-lactamaminoglycoside aac(6')-aph(2"), aph(3')-III , ant(9)-IaST239blaZ, mecAblaZ, mecAaac(6')-aph(2")blaZ, mecAaac(6')-aph(2"), aph(3')-III blaZ, mecAant(6)-Ia, aph(3')-III aac(6')-aph(2")ST239blaZ, mecAblaZ, mecAaph(3')-III blaZ, mecAaac(6')-aph(2"), aph(3')-III blaZ, mecAaac(6')-aph(2")mecAexoenzymessplA, splB, splE, aursplA, splB, splE, aursplA, splB, splE, aursplA, splE, aursplA, splB, splE, auraursplA, splB, splE, aursplA, splB, splE, aursplA, splE, aursplE>8>8>8>8>80.5≤0.25>8≤0.25>8≤0.25>8≤0.250.5>16>1616>1616>161616>16>16≤2≤2≤28≤2≤2≤2≤2≤2≤2>4>40.50.5>40.50.50.50.52tetracyclinemacroridetetMermAtetKtetK, tetMtetKtetKtetKblood cell lysinshlg, lukDEhlghlg, lukDEhlghlg, lukDEhlg, lukDEhlg, lukDEhlg, lukDEhlg, lukDEhlg, lukFS-PV Superantigensseasepseasepseg, sem, sen, seo, seusepsepseg, sei, sem, sen, seo, seutrimethoprimquinolonegyrA(b, parC(bdfrGdfrGgyrA, parCdfrGdfrB(bdfrGgyrA, parCgyrA, parCgyrA, parCdfrGgyrA, parCgyrA, parCgyrA, parC≤32>38/2≤32>38/2≤32>38/2≤32≤9.5/0.5≤32≤9.5/0.5≤32≤9.5/0.5≤32≤9.5/0.5<32>38/2≤32≤9.5/0.5≤32≤9.5/0.5fucidic acidfusA(bfusCfusChostimm(asak, scnsak, scnsak, scnsaksak, scnsak, scnsaksaksak, scn