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1) Johnell O, Kanis JA, Odén A, et al: Mortality after oste-oporotic fractures. Osteoporos Int. 2004; 15: 38-42. 2) Nakamura K: A ‘super-aged’ society and the ‘locomo-tive syndrome’. J Orthop Sci. 2008; 13: 1-2. 3) Lindsay R, Silverman SL, Cooper C, et al: Risk of new vertebral fracture in the year following a fracture. JAMA. 2001; 285: 320-323. 4) Bawa HS, Weick J, Dirschl DR: Anti-Osteoporotic Therapy After Fragility Fracture Lowers Rate of Subsequent Fracture: Analysis of a Large Population muscle strength and quality of life will deteriorate and cannot be restored. In that case, early surgery should be considered.In conclusion, it is important to take measures to prevent subsequent fractures from occurring due to osteoporosis, and it is also important to heal a first osteoporotic vertebral body fracture as soon as possible to allow the patient to return to their normal life.AcknowledgmentsNot applicable.No funding was received.Author contributionsRM analyzed and interpreted the patient data, and was a major contributor in writing the manu-script.Conflicts of interestThe author declare that there are no conflicts of interest.Sample. J Bone Joint Surg Am. 2015; 97: 1555-62. 5) Iba K, Dohke T, Takada J, et al: Improvement in the rate of inadequate pharmaceutical treatment by ortho-paedic surgeons for the prevention of a second fracture over the last 10 years. J Orthop Sci. 2018; 23: 127-131. 6) Hagino H, Sawaguchi T, Endo N, et al: The Risk of a Second Hip Fracture in Patients after Their First Hip Fracture. Calcif Tissue Int. 2012; 90: 14-21. 7) Fujimori K, Tarasawa K, Nakatoh S: Analysis of the persistence and compliance of medications for osteopo-rosis using E-claim database. The Journal of Japan Osteoporosis Society. 2019; 5: 277-285. 8) Dennis MB, John PB, Kristine EE, et al: One year of alendronate after one year of parathyroid hormone (1– 84) for osteoporosis. N Engl J Med. 2005; 353: 555-565. 9) Olivier L, Elena GR, Delphine S, et al: Severe Rebound- Associated Vertebral Fractures After Denosumab Discontinuation: 9 Clinical Cases Report. J Clin Endo-crinol Metab. 2017; 102: 354-358.10) Sinaki M, Itoi E, H. W. Wahner, et al: Stronger back muscles reduce the incidence of vertebral fractures: A Prospective 10 Year Follow-up of postmenopausal Women. Bone. 2002; 30: 836-841.11) Yamazaki S, Ichimura S, Iwamoto J, et al: Effect of walking exercise on bone metabolism in postmeno-pausal women with osteopenia/osteoporosis. J Bone Miner Metab. 2004; 22: 500-508.12) Tsukutani Y, Hagino H, Ito Y, et al: Epidemiology of fragility fractures in Sakaiminato, Japan: incidence, secular trends, and prognosis. Osteoporos Int. 2015; 26: 2249-2255.13) Chen AT, Cohen DB, Skolasky RL: Impact of nonoper-ative treatment, vertebroplasty, and kyphoplasty on survival and morbidity after vertebral compression fracture in the medicare population. J Bone Joint Surg Am. 2013; 95: 1729-1736.14) Edidin AA, Ong KL, Lau E, et al: Morbidity and Mortality After Vertebral Fractures: Comparison of Vertebral Augmentation and Nonoperative Management in the Medicare Population. Spine. 2015; 40: 1228-1241.15) McCullough BJ, Comstock BA, Deyo RA, et al: Major medical outcomes with spinal augmentation vs conser-vative therapy. JAMA Intern Med. 2013; 173: 1514-1521.35FundingReferences

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