68-1

13/98

psychiatric disease. Science, 2015; 349: 1489-94.72) Turro E, Astle WJ, Megy K, et al: Whole-genome sequencing of patients with rare diseases in a national health system. Nature, 2020; 583: 96-102.73) Gur RE, Bassett AS, McDonald-McGinn DM, et al: A neurogenetic model for the study of schizophrenia spectrum disorders: the International 22q11.2 Deletion Syndrome Brain Behavior Consortium. Mol Psychi-atry, 2017; 22: 1664-1672.74) Kendler KS: Phenomenology of Schizophrenia and the Representativeness of Modern Diagnostic Criteria. JAMA Psychiatry, 2016; 73: 1082-1092.75) Smoller JW, Andreassen OA, Edenberg HJ, et al: Psychiatric genetics and the structure of psychopa-thology. Mol Psychiatry, 2019; 24: 409-420.76) Chawner S, Owen MJ, Holmans P, et al: Genotype-phe-notype associations in children with copy number vari-ants associated with high neuropsychiatric risk in the UK (IMAGINE-ID): a case-control cohort study. Lancet Psychiatry, 2019; 6: 493-505.77) Vorstman JA, Breetvelt EJ, Duijff SN, et al: Cognitive decline preceding the onset of psychosis in patients with 22q11.2 deletion syndrome. JAMA Psychiatry, 2015; 72: 377-85.78) Schneider M, Debbane M, Bassett AS, et al: Psychi-atric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome. Am J Psychiatry, 2014; 171: 627-39.79) Stefansson H, Meyer-Lindenberg A, Steinberg S, et al: CNVs conferring risk of autism or schizophrenia affect cognition in controls. Nature, 2014; 505: 361-6.80) Martin-Brevet S, Rodriguez-Herreros B, Nielsen JA, et al: Quantifying the Effects of 16p11.2 Copy Number Variants on Brain Structure: A Multisite Genetic-First Study. Biol Psychiatry, 2018; 84: 253-264.81) Martin CL, Wain KE, Oetjens MT, et al: Identification of Neuropsychiatric Copy Number Variants in a Health Care System Population. JAMA Psychiatry, 2020; 77: 1276-1285.11