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484dilation without sphincterotomy for users of antithrombotic agents: A multicenter retro-spective study. Dig Endosc. 2019; 31: 316-322. 38) Nakai Y, Kogure H, Isayama H, Koike K: Endoscopic ultrasound-guided pancreatic duct drainage. Saudi J Gastroenterol. 2019; 25: 210- 217. 39) Sano M, Ijichi H, Takahashi R, Miyabayashi K, Fujiwara H, Yamada T, Kato H, Nakat-suka T, Tanaka Y, Tateishi K, Morishita Y, Moses HL, Isayama H, Koike K: Blocking CXCLs-CXCR2 axis in tumor-stromal inter-actions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvi-ronment. Oncogenesis. 2019; 8: 8. 40) Sasaki T, Sato T, Nakai Y, Sasahira N, Isayama H, Koike K: Brain metastasis in pancreatic cancer: Two case reports. Medicine (Balti-more). 2019; 98: e14227. 41) Fujisawa T, Saito H, Isayama H: Endoscopic removal of a metal stent that migrated into the peritoneal cavity after endoscopic ultrasound- guided hepaticogastrostomy. Dig Endosc. 2019; 31: e74-e75. 42) Kawaji Y, Isayama H, Nakai Y, Saito K, Sato T, Hakuta R, Saito T, Takahara N, Mizuno S, Kogure H, Matsubara S, Tada M, Kitano M, Koike K: Multiple recurrences after endo-scopic removal of common bile duct stones: A retrospective analysis of 976 cases. J Gastroenterol Hepatol. 2019; 34: 1460-1466. 43) Hakuta R, Hamada T, Nakai Y, Isayama H, Koike K: Pancreatic stent during biliary cannulation: How can we catch 2 hares? Gastrointest Endosc. 2019; 89: 648-649. 44) Hamada T, Isayama H, Nakai Y, Iwashita T, Ito Y, Mukai T, Yagioka H, Saito T, Togawa O, Ryozawa S, Hirano K, Mizuno S, Yama-moto N, Kogure H, Yasuda I, Koike K: Anti-reflux covered metal stent for nonresectable distal malignant biliary obstruction: Multi-center randomized controlled trial. Dig Endosc, 2019; 31: 566-574. 45) Nakai Y, Kogure H, Isayama H, Koike K: Endo-scopic Ultrasound-Guided Biliary Drainage for Benign Biliary Diseases. Clin Endosc, 2019; 52: 212-219. 46) Isayama H, Nakai Y, Itoi T, Yasuda I, Kawakami H, Ryozawa S, Kitano M, Irisawa A, Katanuma A, Hara K, Iwashita T, Fujita N, Yamao K, Yoshida M, Inui K: Clinical prac-tice guidelines for safe performance of endo-scopic ultrasound/ultrasonography-guided biliary drainage: 2018. J Hepatobiliary Pancreat Sci. 2019; 26: 249-269. 47) Saito T, Nakai Y, Mizuno S, Isayama H, Sasa-hira N, Watanabe T, Matsubara S, Arizumi T, Togawa O, Hirano K, Tsujino T, Ishigaki K, Hakuta R, Saito K, Takahara N, Hamada T, Kogure H, Tada M, Koike K: A random-ized-controlled trial of early endotherapy versus wait-and-see policy for mild symp-tomatic pancreatic stones in chronic pancre-atitis. Eur J Gastroenterol Hepatol. 2019; 31: 979-984. 48) Takahara N, Isayama H, Nakai Y, Sasaki T, Saito K, Sato T, Hakuta R, Ishigaki K, Saito T, Hamada T, Mizuno S, Kogure H, Tada M, Koike K: A feasibility study of gemcitabine, S-1 and leucovorin combination therapy (GSL) for advanced biliary tract cancer. J Chemother. 2019; 31: 284-289. 49) Nishiyama M, Ishii S, Fujisawa T, Saito H, Isayama H: Endoscopic removal of a migrated plastic stent from the peritoneal cavity after an EUS-guided gallbladder drainage proce-dure. VideoGIE. 2019; 4: 266-268. 50) Sato T, Kogure H, Nakai Y, Ishigaki K, Hakuta R, Saito K, Saito T, Takahara N, Hamada T, Mizuno S, Yamada A, Tada M, Isayama H, Koike K: Double-balloon endosco-py-assisted treatment of hepaticojejunos-tomy anastomotic strictures and predictive factors for treatment success. Surg Endosc, 2019 Jun 19. [Epub ahead of print] 51) Gonoi W, Okuma H, Hayashi TY, Akahane M, Nakai Y, Tateishi R, Mizuno S, Suzuki Y, Mitsuda M, Matsuda K, Nakagawa K, Isayama H, Miyagawa K, Koike K, Abe O: Development of pancreatic cancer during observation for hepatocellular carcinoma: A retrospective cohort study. Saudi J Gastroen-terol. 2019; 25: 390-396. 52) Seo DW, Sherman S, Dua KS, Slivka A, Roy A, Costamagna G, Deviere J, Peetermans J, Rousseau M, Nakai Y, Isayama H, Kozarek R:

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